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目的观察麻黄碱预防剖宫产术仰卧位低血压综合征的临床效果。方法选择420例剖宫产产妇作为研究对象,随机分为观察组及对照组各210例,产妇进入手术室后静脉进行开放后对照组麻醉前快速滴入乳酸钠林格液500 mL,实施腰麻-硬膜外联合麻醉;观察组肌注麻黄碱20 mg,然后实施腰麻-硬膜外联合麻醉。结果 2组产妇均顺利完成手术,术前平均动脉压、心率无显著性差异(P>0.05);观察组术中平均动脉压高于对照组,心率、低血压发生率、不良反应低于对照组(P<0.01)。结论预防性注射麻黄碱可以明显减少腰麻-硬膜外联合麻醉低血压的发生率及血压的下降幅度,使剖宫产产妇在整个手术过程中血压、心率处于平稳状态,有显著的临床应用价值。
Objective To observe the clinical effect of ephedrine in preventing supine hypotension syndrome in cesarean section. Methods 420 cases of cesarean section were selected as study subjects and randomly divided into observation group and control group with 210 cases each. When the mother entered the posterior chamber of the operating room, 500 ml sodium lactate Ringer’s solution was rapidly dripped into the control group before anesthesia. - epidural anesthesia; intramuscular injection of ephedrine 20 mg, and then the implementation of spinal anesthesia - epidural anesthesia. Results The average arterial pressure and heart rate of the two groups were all significantly improved (P> 0.05). The average arterial pressure in the observation group was higher than that in the control group. The incidence of heart rate and hypotension was lower than that of the control group Group (P <0.01). Conclusion Ephedrine prophylaxis can significantly reduce the incidence of spinal anesthesia - epidural anesthesia hypotension and blood pressure decline so that cesarean section during the entire operation blood pressure and heart rate in a steady state, a significant clinical application value.