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早产常造成高新生儿病率和死亡率,本病由多因素引起,本文综述亚临床感染导致早产的有关证据。组织学的羊膜绒毛膜炎与早产有关,但机理尚需进一步研究。组织学的羊膜绒毛膜炎与早产的羊膜绒毛膜炎的关系有待加强研究。早产未破膜病人羊水培养阳性率为0%~30%.尚不清楚这是导致早产的原因还是早产的结果。某些早产病人血C-反应蛋白和羊水中异常有机酸水平升高,提示有亚临床感染。有感染的早产病例,前列腺素及其代谢产物、内毒素和细胞活素的体内-外研究结果提示早产的某些生物化学机理。应进一步研究感染引起早产的机理及预防途径。
Premature birth often causes high neonatal morbidity and mortality, the disease is caused by many factors, this article reviews the evidence of subclinical infection leading to preterm birth. Histological amniotic choriocarcinoma and premature delivery, but the mechanism needs further study. The relationship between histological amniotic chorioamnion and preterm labor of amniotic chorioamnitus needs further study. The positive rate of amniotic fluid culture in patients with unruptured prematurity is 0% to 30%. It is unclear whether this is the cause of preterm birth or the result of premature delivery. Some preterm patients with elevated serum C-reactive protein and amniotic fluid levels of organic acids, suggesting subclinical infection. In-vitro studies of preterm births, prostaglandins and their metabolites, endotoxins and cytokines in infected individuals suggest some of the biochemical mechanisms of preterm birth. Should further study the mechanism of infection caused by premature delivery and prevention.