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肥大细胞是哮喘速发反应中的主要效应细胞,而它在哮喘迟发反应中的作用尚未明确,这主要是由于在肥大细胞缺陷小鼠变应性哮喘模型中的研究结果很不一致,实验方法对评价肥大细胞在气道反应性和嗜酸粒细胞气道炎症中的作用有很大影响。
Mast cells are the major effector cells in the immediate asthmatic response and its role in the delayed response to asthma is unclear, largely due to the inconsistent results in the model of allergic asthma in mast cell-deficient mice. Experimental methods It has a great impact on the evaluation of the role of mast cells in airway responsiveness and eosinophilic airway inflammation.