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作者在15年前开始了一项对大批充分确定有正常肝化学特性的慢性HBsAg携带者人群的长期随访研究。本文报告平均随访期约11年的结果。研究组包括92例(75例男性和17,例女性)HBsAg阳性而肝功能正常的供血者,年龄19～56岁,平均31.5岁。这些病人在编入研究组之前6～60个月首次发现HBsAg阳性。采集血标本检测HBV标志和肝酶水平;回顾性地检测贮存血清标本的HBV DNA、抗-HD和抗-HCV。按标准技术对病人作经
The authors started a long-term follow-up study 15 years ago on a large population of well-established chronic HBsAg carriers with normal liver chemistry. This article reports the results of an average follow-up of approximately 11 years. The study group consisted of 92 donors (75 males and 17 females) with positive HBsAg and normal liver function, aged 19- 56 years (average 31.5 years). These patients were the first to find HBsAg positive 6 to 60 months prior to enrollment in the study group. Blood samples were collected for detection of HBV markers and liver enzymes; HBV DNA, anti-HD and anti-HCV were also retrospectively analyzed. According to standard techniques for patients