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目的:探讨肾脏病患儿血清微量元素含量的改变及相关规则。方法:采用电感耦合等离子体原子发射光谱(ICP—AES)法测定肾脏病患儿血清微量元素的含量。结果:单纯性肾病组、肾炎性肾病组、紫癜性肾病组及肾炎组血清中锌均显著低于正常对照组(P<0.05)。血清中铁、镁与正常对照组比较无显著性差异(P>0.05),单纯性肾病组、紫癜性肾病组血清中铜显著低于正常对照组(P<0.05)。结论:微量元素含量的变化与小儿肾脏疾病的发生及状态有关,其代谢的紊乱和缺乏可引发肾脏疾病,及时补充和调整微量元素对肾脏疾病具有重要的意义。
Objective: To investigate the changes of serum trace elements in children with kidney disease and related rules. Methods: The contents of trace elements in children with kidney disease were measured by inductively coupled plasma atomic emission spectrometry (ICP-AES). Results: The levels of serum zinc in simple nephropathy group, nephritis nephropathy group, purpuric nephropathy group and nephritis group were significantly lower than those in normal control group (P <0.05). Serum levels of iron and magnesium had no significant difference compared with the normal control group (P> 0.05). The serum levels of copper in the simple nephropathy group and purpuric nephropathy group were significantly lower than those in the normal control group (P <0.05). CONCLUSION: The change of trace element content is related to the occurrence and status of kidney disease in children. The disorder and deficiency of metabolism can cause kidney disease, and timely replenishment and adjustment of trace elements are of great significance to kidney disease.