目的对妇产科手术围手术期生殖道感染抗生素的应用情况进行观察分析。方法将110例妇产科手术患者随机分为观察组(55例)与参考组(55例),观察组患者术前预防性给予抗生素,参考组患者手术前后均给予抗生素,对两组患者术后感染发生情况进行观察比较。结果观察组术后感染发生率为14.5%,参考组术后感染发生率为12.7%,差异比较无统计学意义(P>0.05);两组患者感染部位主要为切口感染、发热、呼吸道感染、生殖道感染等。结论术前给予患者抗生素能够起到预防术后感染的作用,能够有效减少患者医疗费用,同时减少抗生素过量使用导致的不良后果。 Objective To observe and analyze the application of antibiotics in perioperative genital tract infection in obstetrics and gynecology. Methods 110 cases of obstetrics and gynecology surgery were randomly divided into observation group (55 cases) and reference group (55 cases). Patients in observation group were given prophylactic antibiotics preoperatively, patients in reference group were given antibiotics before and after operation, After the occurrence of infection were observed and compared. Results The incidence of postoperative infection was 14.5% in the observation group and 12.7% in the reference group. There was no significant difference between the two groups (P> 0.05). The infection sites in the two groups were incisional infection, fever, respiratory infection, Genital tract infections. Conclusion Preoperative antibiotics given to patients can play a role in preventing postoperative infection, can effectively reduce the medical costs of patients, while reducing the adverse consequences of antibiotic overuse.