凋亡抑制与肝癌发生上田启次等在ＨＢＶ基因组克隆成功以来的近十年里，由于分子生物学技术的长足进展，已可从ＨＢＶ标志阳性肝癌几乎１００％检出有ＨＢＶ－ＤＮＡ整合。然而，决不等于说有此种整合即要肝脏发癌，这在实验水平上也未获得证实，甚至从生物学上理解也还远... Apoptosis inhibition and hepatocarcinogenesis In the past ten years since the HBV genome was successfully cloned, etc., HBV-DNA integration has been detected in almost 100% of HBV-marker-positive liver cancers due to the rapid progress in molecular biology techniques. However, it is by no means equal to saying that there is such integration that is to cause cancer in the liver, which has not been confirmed at the experimental level, and even understood biologically far...