论文部分内容阅读
目的了解新疆生产建设兵团第二师0~6岁儿童麻疹血清抗体水平,为制定免疫预防对策提供依据。方法按照随机抽样原则,2012年调查第二师所属5个团场0~6岁儿童共483人,采用酶联免疫吸附试验(ELISA)检测血清麻疹IgG抗体。结果麻疹IgG抗体阳性率为88.20%,麻疹抗体几何平均滴度(GMT)748;不同性别麻疹抗体阳性率及GMT差异无统计学意义(χ2=3.56,F=3.72,P>0.05);不同年龄抗体阳性率、GMT差异均有统计学意义(χ2=19.51,F=5.42,P<0.01);不同地区抗体阳性率、GMT差异亦均有统计学意义(χ2=29.07,F=63.02,P<0.01)。结论 0~6岁儿童免疫状况良好,短期内麻疹流行可能性较小,但应加强1岁以上幼儿和流动儿童麻疹疫苗的常规免疫和强化免疫及补种工作。
Objective To understand the level of measles antibody in children from 0-6 years old in the second division of Xinjiang Production and Construction Corps and provide basis for developing immunoprophylaxis. Methods In accordance with the principle of random sampling, a total of 483 children aged 0-6 years from 5 teams in the second division were investigated in 2012, and serum anti-IgG was detected by enzyme-linked immunosorbent assay (ELISA). Results The positive rate of measles IgG was 88.20%, and the geometric mean of measles antibody was 748. There was no significant difference in the positive rate of measles antibody and GMT between different sex (χ2 = 3.56, F = 3.72, P> 0.05) (Χ2 = 19.51, F = 5.42, P <0.01). The antibody positive rates and GMT differences in different regions were also statistically significant (χ2 = 29.07, F = 63.02, P < 0.01). Conclusions Children aged 0-6 are in good immunization status and the possibility of measles is less likely in the short term. However, routine immunization, intensive immunization and vaccination should be strengthened for children over 1 year of age and migrant children.