作者报道,用少量的甲醇钠作催化剂,将毛花洋地黄甙进行甲醇分解反应,可得脱乙酰毛花洋地黄甙。本法不论在产量或分离操作方面均优于其他水解方法。方法:将毛花洋地黄甙C5000毫克加于10~(-2)M甲醇钠的甲醇溶液100毫升中,在室温22°放置4小时,即可完全脱乙酰基。用几滴冰醋酸中和甲醇钠,蒸去甲醇,脱乙酰 The authors report that using a small amount of sodium methoxide as a catalyst, the flowering digitalis glycoside was subjected to a methanolysis reaction to obtain deacetylated flowen digoxigenin. This Law is superior to other hydrolysis methods in terms of yield or separation. Methods: The genistin C5000 mg was added to 100 ml methanol solution of 10 ~ (-2) M sodium methoxide, and then completely deacetylated at room temperature for 4 hours at 22 °. Neutralize sodium methoxide with a few drops of glacial acetic acid, steam to methanol, and deacetylate