论文部分内容阅读
最新研究认为 ,人甲胎蛋白 (ｈＡＦＰ)具有促进原发性肝癌(ＰＨＣ)生成、发展的生物学功能。运用ｈＡＦＰ的单克隆抗体与抗肿瘤药物偶联 ,既可以达到肝癌导向治疗的目的 ,又可通过降低血清和肝癌组织中ｈＡＦＰ含量 ,达到拮抗ｈＡＦＰ的促癌作用。我们制备了一株ｈＡＦＰ单克隆
Recent research suggests that human alpha-fetoprotein (hAFP) has the biological function of promoting the formation and development of primary liver cancer (PHC). Monoclonal antibodies conjugated with anti-tumor drugs using hAFP can not only achieve the goal of hepatocarcinoma-directed therapy, but also inhibit the hAFP-promoting cancer effect by decreasing hAFP levels in serum and liver cancer tissues. We made a single hAFP clone