药物与剂量同是影响方剂疗效的两大因素,药物组成相同的方剂,在剂量或配比不同时疗效迥异,日本学人渡边熙说:“汉药之秘,不可告人者,即在药量。”因此,在新药研发过程中,重要任务之一就是寻找能够提升复方疗效、使多个药效指标达到综合最优的药量与比例,这一研究,被称为“复方 Drugs and doses are the two major factors affecting the efficacy of prescriptions. Drugs that make up the same formula have different effects at different doses or ratios. Japanese scholar Watanabe Hee said: “The secret of Chinese medicine is not to be sued, that is, Drug dosage.” Therefore, one of the important tasks in the development of new drugs is to search for drug doses and proportions that can improve the efficacy of the compound and achieve multiple optimal drug efficacy indicators. This study is called “compounding.”