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C4’-H bond dissociation enthalpies of nucleosides were predicted using theoretical methods to a precision of 1-2 Kcal/mol. It was found that the stability of the C4’ nucleoside radical is slightly dependent on the base. The orders of stability are dA < dG < dT < dC for deoxynucleosides and U < G < A = C for nucleosides.
C4’-H bond dissociation enthalpies of nucleosides were predicted using theoretical methods to a precision of 1-2 Kcal / mol. It was found that the stability of the C4 ’nucleoside radical is slightly dependent on the base. The orders of stability are dA
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