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目的分析国内不同地域的儿童血铅和尿铅同位素比值特征,并探讨同体血液和尿液铅同位素比值间的相关性。方法从山西和云南两区域抽取3~14岁儿童264名,按照国家有关标准和规范的要求采集被调查儿童的血液和尿液样品,使用电感耦合等离子体质谱(ICP-MS)法对采集样品进行铅同位素比值测定。结果山西和云南被调查地区儿童的3个血铅同位素比值(204Pb/206Pb、207Pb/206Pb和208Pb/206Pb)显著不同(P<0.01);而同体血铅和尿铅的同位素比值则不具有相关性(r值分别为-0.105、0.052和0.363,P值分别为0.641、0.818和0.097)。结论不同地域儿童血铅同位素比值不同,同一地域内临近城镇的儿童血铅同位素比值特征也有一定差别,同体尿铅和血铅的同位素比值不具有显著相关性。
Objective To analyze the characteristics of blood lead and urinary lead isotope ratio in different regions of China and to explore the correlation between the blood lead and urine urine isotope ratio. Methods A total of 264 children aged 3-14 years were collected from Shanxi and Yunnan Provinces. Blood and urine samples of children were collected according to relevant national standards and norms, and samples were collected by inductively coupled plasma mass spectrometry (ICP-MS) Lead isotope ratio determination. Results The three blood lead isotope ratios (204Pb / 206Pb, 207Pb / 206Pb and 208Pb / 206Pb) were significantly different in children surveyed in Shanxi and Yunnan (P <0.01), while the isotope ratios of blood lead and urine lead were not correlated (R values were -0.105, 0.052 and 0.363 respectively, P values were 0.641, 0.818 and 0.097, respectively). Conclusions The blood lead isotope ratios of children in different regions are different. Children’s blood lead isotope ratio is also different in the same area. There is no significant correlation between the isotope ratio of urinary lead and blood lead.