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目的提高颅内胆脂瘤的诊断水平与手术治疗效果。方法总结分析218例颅内胆脂瘤的临床征象、诊断方式、显微手术入路与疗效。结果203例（93．1％）肿瘤获全切除，余15例（6．9％）因肿瘤包膜与丘脑或脑干粘连紧密而行次全切除。5例（2．3％）于手术后2周内因脑干缺血、水肿或肺部感染死亡。176例获长期随访（平均5．6年），其中170例（96．6％）恢复良好，3例（1．7％）肿瘤有复发，需行再次手术切除。结论采用CT或MRI进行诊断并用显微手术治疗颅内胆脂瘤，是一种行之有效的方法。
Objective To improve the diagnosis of intracranial cholesteatoma and surgical treatment. Methods The clinical manifestations, diagnosis, microsurgery approach and curative effect of 218 cases of intracranial cholesteatoma were analyzed. Results Totally 203 (93.1%) tumors were resected and the remaining 15 (6.9%) were subtotally resected due to the close adhesion of the tumor capsule to the thalamus or brainstem. Five patients (2.3%) died of brain stem ischemia, edema or pulmonary infection within 2 weeks after surgery. A total of 176 patients were followed up for an average of 5.6 years (170 patients (96.6%) recovered well and 3 patients (1.7%) had a recurrence of tumor requiring reoperation. Conclusion CT or MRI diagnosis and microsurgical treatment of intracranial cholesteatoma is an effective method.