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尿石症是泌尿外科常见病之一,但动物模型的报导少见。本文采用药物诱发技术,对用大鼠复制泌尿系结石模型进行了初步探讨。材料和方法一、材料 1.动物:SD大鼠53只,雌雄兼用,12～14周龄,体重230±10.5g。在实验室饲育一周后,随机分为实验组和对照组。 2.1.2％乙二酰胺——标准药饵:饲料配方:30％豆粉,30％面粉,20％玉米粉,6％鱼粉,1％青油,0.5％维生素,1％酵母粉,9％麸皮,1.5％骨粉,1％食盐。取经60～8O℃干烤饲料988g,加入乙二酰胺12g,充分拌匀备用。作为诱发泌尿系结石药饵,简称药饵。
Urolithiasis is one of the common urological diseases, but reports of animal models are rare. In this paper, the use of drug-induced technology, rat urinary calculus model was first explored. Materials and Methods First, the material 1. Animals: 53 SD rats, both male and female, 12 to 14 weeks of age, weighing 230 ± 10.5g. After a week of feeding in the laboratory, they were randomly divided into experimental group and control group. 2.1.2% ethanediamide - standard bait: feed formula: 30% soybean meal, 30% flour, 20% corn meal, 6% fish meal, 1% Bran, 1.5% bone meal, 1% salt. Take 60 ~ 8O ℃ dry roasted feed 988g, adding oxalic acid 12g, mix well and spare. Urinary tract stones as bait induced, referred to as bait.