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对于所有的癌肿,早期发现才会有较好的治疗效果,但大多数食管癌发现时已属进展期,小的食管病变,尤其是上皮内癌很难发现。随着内镜技术的发展和改进以及内镜直视下活检的广泛应用,早期食管癌诊断的病例愈来愈多。自1985年以来,作者做内镜检查发现食管粘膜异常时,采用 Lugol 液染色并取怀疑部位活检。平坦的病变常无颜色改变或可能表现为一个红点,内镜下可清楚地观察到这些病变 Lugol 染色不着染。通过该技术共发现6例上皮癌、3例粘膜癌、75例粘膜下癌,表明内镜下 Lugol 染色并活检是现今发现小的食管癌的、最有效的诊断方法。在大多数情况下,这类病变常常是
For all cancers, early detection will have a better therapeutic effect, but most esophageal cancers are already in advanced stages, and small esophageal lesions, especially intraepithelial cancers, are difficult to find. With the development and improvement of endoscopic technology and the wide application of biopsy under endoscopy, more and more cases of early esophageal cancer are diagnosed. Since 1985, when the authors performed an endoscopy to find abnormalities of the esophageal mucosa, they were stained with Lugol’s fluid and biopsied at suspected sites. Flat lesions often have no color change or may appear as a red dot, and these lesions are clearly observable under endoscopy with Lugol staining. A total of 6 cases of epithelial cancer, 3 cases of mucosal cancer, and 75 cases of submucosal cancer were detected by this technique, indicating that endoscopic Lugol staining and biopsy are the most effective diagnostic methods for the detection of small esophageal cancer. In most cases, such lesions are often