Rb基因（retinoblastomagene，Rb）是一重要的抑癌基因，其编码的Rb蛋白在细胞周期中发挥调控作用。近年已发现人类多种肿瘤中Rb基因结构异常，其异常表达与某些肿瘤的发生有关。有关Rb蛋白表达与基因突变关系的报道较少见。我们曾用PCR．SSCP法分析了胃癌Rb基因部分外显子的突 The Rb gene (Rb) is an important tumor suppressor gene, and its encoded Rb protein plays a regulatory role in the cell cycle. In recent years, it has been found that many human tumors in the Rb gene structure abnormalities, the abnormal expression of some tumors. Rb protein expression and gene mutation is rarely reported. We used PCR. SSCP analysis of gastric cancer Rb gene exons of sudden