论文部分内容阅读
目的:通过对平原地区与高原地区慢性阻塞性肺疾病(COPD)患者合并肺间质纤维化(PF)的高分辨率CT(HRCT)图像资料进行分析,探讨高原地区COPD合并肺间质纤维化的HRCT特点及高原环境对PF的发病情况的影响。方法:收集平原组海拔(200~600)m及高原组海拔(3 100~4 500)m临床确诊的COPD患者各100例,观察两组病例高分辨率CT(HRCT)图像特征,并对两个地区COPD患者中PF发病率进行统计学处理。结果:COPD合并肺间质纤维化的HRCT表现包括支气管炎、肺气肿及肺间质改变,肺间质改变主要有小叶间隔增厚、网状影、磨玻璃影及蜂窝状影;平原组COPD 100例,PF发生19例,发病率为19%,高原组COPD 100例,PF发生37例,发病率为37%,两组之间比较,差异有统计学意义(x~2=4.723,P<0.05)。结论:高原地区COPD患者中PF的发病率显著高于平原地区,而且影像学表现更为严重、更为明显;HRCT对诊断COPD合并PF具有重要的影像学价值。
OBJECTIVE: To analyze high resolution CT (HRCT) image data of patients with chronic obstructive pulmonary disease (COPD) complicated with pulmonary interstitial fibrosis (PF) in plain and plateau areas and to explore the relationship between COPD and pulmonary fibrosis HRCT characteristics and the impact of plateau on the incidence of PF. Methods: The clinical data of 100 patients with clinically diagnosed COPD at altitude of 200-600 m in plain group and altitude of 3 100-4 500 m in plateau group were collected. The features of high resolution CT (HRCT) images in both groups were observed. The incidence of PF in patients with COPD was statistically analyzed. Results: The HRCT findings of COPD with pulmonary fibrosis include bronchitis, emphysema and interstitial lung changes. The changes of interstitial lung mainly include interlobular septal thickening, reticular shadow, ground glass shadow and honeycomb shadow. The plain group 100 cases of COPD, 19 cases of PF, 19 cases of COPD, 100 cases of COPD in plateau group and 37 cases of PF, the incidence was 37%. The difference was statistically significant (x ~ 2 = 4.723, P <0.05). CONCLUSION: The incidence of PF in patients with COPD is significantly higher in the plateau region than in the plain region, and the imaging findings are more serious and more obvious. HRCT has important imaging value in the diagnosis of COPD with PF.