论文部分内容阅读
目的:研究舒芬太尼混合左旋布比卡因在小儿骶管阻滞术后镇痛的效果与安全性。方法:选择100例ASAⅠ级、年龄3～6岁、择期行斜疝高位结扎修补手术患儿,随机分为,四组麻醉,每组25例;Ⅰ组骶管注入0.375%左旋布比卡因+舒芬太尼1μg·ml~(-1)混合液,Ⅱ组骶管注入0.375%左旋布比卡因+吗啡50μg·ml~(-1)混合液,Ⅲ组骶管注入0.375%左旋布比卡因+芬太尼5μg·ml~(-1)混合液,Ⅳ组骶管注入0.375%左旋布比卡因。术后1,3,5,8,12,24 h观察患儿的血压、心率、呼吸、脉搏血氧饱和度,评定镇痛效果及术后运动功能;观察并记录不良反应情况。结果:术后3、5、8 h,Ⅰ组、Ⅱ组、Ⅲ组的镇痛效果与Ⅳ组对比有统计学意义;术后8、12、24 hⅠ组、Ⅱ组的镇痛效果与Ⅲ组、Ⅳ组对比有统计学意义。Ⅱ组患儿不良反应率较高。结论:舒芬太尼混合左旋布比卡因注入小儿骶管行术后镇痛效果好、安全性高,不良反应少。
Objective: To study the efficacy and safety of sufentanil combined with levobupivacaine for postoperative analgesia in children with caudal block. Methods: A total of 100 children with ASA grade I, aged 3 to 6 years old, undergoing elective lumbar hernia repair surgery were randomly divided into four groups of anesthesia in each group of 25 cases. Group Ⅰ was injected with 0.375% levobupivacaine + Sufentanil 1μg · ml ~ (-1) mixture, group Ⅱ caudal injection of 0.375% levobupivacaine + morphine 50μg · ml ~ (-1) mixture, group Ⅲ caudal injection of 0.375% Pika + fentanyl 5μg · ml ~ (-1) mixture, Ⅳ group caudal injection of 0.375% levobupivacaine. Blood pressure, heart rate, respiration and pulse oximetry were observed at 1, 3, 5, 8, 12 and 24 hours after operation. Analgesic effect and postoperative motor function were evaluated. Adverse reactions were observed and recorded. Results: At 3, 5 and 8 h after operation, the analgesic effects of group Ⅰ, group Ⅱ and group Ⅲ were statistically significant compared with group Ⅳ. The analgesic effects of group Ⅰ and group Ⅱ at 8, 12 and 24 h after operation were similar to those of group Ⅲ Group, Ⅳ group was statistically significant. Adverse reactions in group Ⅱ were higher. Conclusion: Sufentanil mixed levobupivacaine infused into pediatric sacral line has good analgesic effect, high safety and few adverse reactions.