Tenascin-W是Tenascin家族中的一员,是一种黏附抑制因子。正常组织中不表达Te-nascin-W,因此Tenascin-W作为肿瘤标志物的研究更具有广泛的前景。Tenascin-W能促进肿瘤细胞及肿瘤相关细胞的迁移,以此干预肿瘤细胞的生物学行为,在肿瘤新生血管也检测到了Tenascin-W,推测其可能通过抑制癌细胞的黏附,加速肿瘤新生血管的形成,促进了肿瘤的侵袭转移,加速了肿瘤细胞的恶性进展。 Tenascin-W is a member of the Tenascin family and is an adhesion inhibitor. The normal tissue does not express Te-nascin-W, so Tenascin-W as a tumor marker has more extensive prospects for the study. Tenascin-W can promote the migration of tumor cells and tumor-related cells in order to interfere with the biological behavior of tumor cells. Tenascin-W was also detected in tumor neovascularization, presumably by accelerating tumor angiogenesis by inhibiting the adhesion of cancer cells Formation, promote the invasion and metastasis of the tumor, accelerated the malignant progress of tumor cells.