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钙拮抗剂(Ca-A)与神经、呼吸以及心血管系统疾病有密切关系。八十年代后 Ca-A 与胃肠道疾病的关系日益受到人们的重视,本文综述其有关文献。Ca-A 与食管疾病Ca-A 可抑制氯化钾或胆碱能药物刺激的离体兔食管下段括约肌的收缩。然而,硫氮(艹卓)酮(diltiazem)较异搏停(verapamil)的抑制更为明显。Ca-A 可用于食管疾患的治疗。有学者对7名正常人应用硝苯吡啶(nifedipin)20mg 舌下含服,可降低食管下段括约肌的压
Calcium antagonists (Ca-A) and nerve, respiratory and cardiovascular diseases are closely related. Since the 1980s, the relationship between Ca-A and gastrointestinal diseases has been paid more and more attention by people. This article reviews its literature. Ca-A and esophageal disease Ca-A can inhibit the contractile contraction of the lower esophageal sphincter stimulated by potassium chloride or cholinergic drugs. However, the inhibition of diltiazem over verapamil is even more pronounced. Ca-A can be used for the treatment of esophageal disorders. Some scholars on the seven normal use of nifedipine (nifedipin) 20mg sublingual, can reduce the pressure of the lower esophageal sphincter