论文部分内容阅读
目的探讨更昔洛韦治疗小儿轮状病毒肠炎患儿的发热、腹泻、呕吐等临床表现的疗效及安全性。方法60例8个月～3岁患轮状病毒感染的患儿随机分为治疗组(更昔洛韦)和对照组(炎琥宁)。观察2组治疗前、后发热、吐泻、脱水及电解质紊乱结合变化。结果治疗组,对照组治疗后发热、呕吐、脱水、腹泻次数,血、便常规改变均较治疗前明显减轻,治疗后,更昔洛韦组退热轮状病毒转阴和腹泻次数好转平均时间优于对照组,(P<0.05)。治疗3d后消化道症状的改善总有效率高于对照组。结论更昔洛韦治疗小儿轮状病毒肠炎疗效显著。
Objective To investigate the efficacy and safety of ganciclovir in the treatment of children with rotavirus enteritis in children with fever, diarrhea and vomiting. Methods Sixty children aged 8 months to 3 years old with rotavirus infection were randomly divided into treatment group (ganciclovir) and control group (yanhuning). Two groups were observed before and after treatment, fever, vomiting, dehydration and electrolyte imbalance combined changes. Results After treatment, the incidence of fever, vomiting, dehydration, diarrhea, blood and routine changes in treatment group and control group were significantly reduced compared with those before treatment. After treatment, the number of negative rotavirus and diarrhea in ganciclovir group improved Better than the control group (P <0.05). The total effective rate of improvement of gastrointestinal symptoms after 3 days of treatment was higher than that of the control group. Conclusion Ganciclovir treatment of pediatric rotavirus enteritis has a significant effect.