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Ｇｅ－１３２赖氨酸盐２００ｍｇ·ｋｇ－１·ｄ－１×１０ｄ及１００ｍｇ·ｋｇ－１·ｄ－１×１０ｄｉｇ对小鼠移植性Ｓ１８０荷瘤实体瘤的抑制率分别为４６．７％、３４．７％，对小鼠移植性Ｈ２２肝癌实体瘤的抑制率分别为４２．５％、３５．２％。２００ｍｇ·ｋｇ－１·ｄ－１×１５·ｄ及１００ｍｇ·ｋｇ－１·ｄ－１×１５ｄｉｇ对小鼠移植性ＬＬＣ肺癌实体瘤的抑制率分别为８１．７％、６１．７％，其抑制率均高于Ｇｅ－１３２同剂量组。Ｇｅ－１３２赖氨酸盐对Ｈ２２肝癌腹水型小鼠的生命延长率明显大于ＮＳ组及Ｇｅ－１３２组。提示Ｇｅ－１３２赖氨酸盐的抗癌作用比Ｇｅ－１３２更明显。
The inhibitory rates of Ge-132 lysine 200mg · kg-1 · d-1 × 10d and 100mg · kg-1 · d-1 × 10dig on the transplanted S180 tumor-bearing solid tumor in mice were 46.7% 34.7%. The inhibitory rates of transplanted H22 hepatoma solid tumor in mice were 42.5% and 35.2%, respectively. The inhibitory rates of 200mg · kg-1 · d-1 × 15 · d and 100mg · kg-1 · d-1 × 15dig were 81.7% and 61.7%, respectively The inhibitory rates were higher than Ge-132 same dose group. Life prolongation of Ge-132 lysine salt to H22 hepatocellular carcinoma ascites mice was significantly longer than NS and Ge-132 groups. The anti-cancer effect of Ge-132 lysine salt is more obvious than that of Ge-132.