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目的 探讨侧支循环形成与急性ST段抬高型心肌梗死(STEMI)患者心肌无复流的相关性. 方法 回顾2013年6月—2017年12月接受急诊经皮冠状动脉介入治疗(PCI)的STEMI患者227 例,根据心肌梗死溶栓治疗临床试验(TIMI)血流是否等于3级分为正常血流组和无复流组,其中无复流组33 例,正常血流组194 例.结果 (1)无复流组与正常血流组相比侧支循环形成更多(P＜0.001).(2)多因素Logistic回归分析显示:冠脉内注射替罗非班、吸烟、卒中、血小板计数和侧支循环形成是无复流发生的独立危险(保护)因素.结论 STEMI患者急诊PCI术后侧支循环形成可以减少无复流发生.“,”Objective To investigate the relationship between coronary collateral circulation and myocardial no-reflow (MNR) in patients with ST-segment elevation myocardial infarction (STEMI) after primary percutaneous coronary intervention (PCI). Methods 227 STEMI patients who were treated by the PCI from June 2013 to December 2017 in hospital were divided into MNR group and control group, and their clinical data were statistically analyzed. MNR was defined as TIMI ≤ grade 2, including 33 patients with MNR and 194 controls. Results (1)The STEMI patients with MNR were positively associated with coronary collateral circulation, where the difference between groups is statistically significant (P＜0.001). (2)Multifactorial Logistic regression analysis showed that intravascular injection of tirofiban, smoking, stroke, platelet count and coronary collateral circulation are independent predictor of MNR. Conclusion Coronary collateral circulation decrease the possibility for patients of MNR after PCI.