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β_2微球蛋白(β_2m)系由100个氨基酸组成的一个单链的低分子蛋白质,是HLA抗原的一部分为代表恒定的轻链,存在于所有带核的细胞膜上,其在血清和尿液中浓度,可用于监测肾小球性及肾小管性肾疾病。在慢性炎症病灶和肿瘤时,血清β_2m水平可增高。本文作者对肾细胞癌患者术前血清β_2m水平作观察,对40例肾细胞癌患者观察血清β_2m值,(男性27例,女性13例),年龄33～79岁,平均54.8岁。血标本均在术前采集,以排除因肾功能损害所造成的假阳性,同样,血清肌酐超过1.4mg/dl不在本研究之内(3/43=7%)。患者按肿瘤分期分组如下:4例
Β_2 microglobulin (β_2m) is a single-stranded, low-molecular protein consisting of 100 amino acids that is part of the HLA antigen and represents a constant light chain present on all nucleated cell membranes, in serum and urine Concentration can be used to monitor glomerular and tubular renal disease. In chronic inflammatory lesions and tumors, serum β 2m levels may increase. The authors observed preoperative serum β 2 m levels in renal cell carcinoma patients and observed serum β 2 m values in 40 renal cell carcinoma patients (27 males and 13 females), aged 33 to 79 years, with an average of 54.8 years. Blood specimens were collected preoperatively to rule out false positives due to renal impairment. Similarly, serum creatinine exceeding 1.4 mg/dl was not included in this study (3/43 = 7%). Patients were grouped according to tumor stage as follows: 4 cases