近年来对该病进行了广泛研究 ,但其发病机理尚不清楚。为了搞清肾综合征出血热病毒 (ＨＦＲＳＶ)对肾组织的损伤机理 ,本文首次选用易饲养、敏感、高效的人胚肾原代细胞直接攻击ＨＦＲＳＶ。为确保结果的准确性 ,改用了胶原酶温和消化法 ,取得令人满意的结果。现将结果报告如下 In recent years, the disease has been extensively studied, but its pathogenesis is not clear. In order to find out the mechanism of kidney damage caused by hemorrhagic fever with renal syndrome (HFRSV), this study, for the first time, used HFRSV to challenge HFRSV directly by easy-to-raise, sensitive and efficient primary human embryonic kidney cells. In order to ensure the accuracy of the results, we switched to the mild digestion of collagenase and achieved satisfactory results. The results reported below