论文部分内容阅读
目的:探讨COPD-PIF(慢性阻塞性肺疾病,肺间质纤维化)患者的临床表征。方法:以该院COPD-PIF患者84例,特发性肺间质纤维化(IPF)60例患者为对象,观察其临床症状、肺功能以及血气分析情况。结果:IPF组:FEV1(%Pred)、FEV1(%)的占比较慢性COPD-IPF组患者更高,而FVC(%Pred)则较慢性COPD-PIF组更低;IPF组低氧血症发生率71.43%低于慢性COPD-PIF组61.90%,差异性明显(P<0.05)。结论:当COPD患者伴有低氧血症或者是呼吸衰竭,需防范COPD-PIF;HRCT对临床诊断COPD-PIF具有较高的灵敏度。
Objective: To investigate the clinical features of COPD-PIF (chronic obstructive pulmonary disease, pulmonary fibrosis). Methods: Eighty-four patients with COPD-PIF and 60 patients with idiopathic pulmonary fibrosis were enrolled in this study. Clinical symptoms, pulmonary function and blood gas analysis were observed. Results: In IPF group, FEV1 (% Pred) and FEV1 (%) were higher than those in chronic COPD-IPF group, while FVC (% Pred) was lower than that in chronic COPD-PIF group. Hypoxemia occurred in IPF group The rate of 71.43% was lower than that of the chronic COPD-PIF group (61.90%), the difference was significant (P <0.05). Conclusion: COPD-PIF should be prevented when patients with COPD are accompanied by hypoxemia or respiratory failure. HRCT has high sensitivity for clinical diagnosis of COPD-PIF.