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目的探讨中西药结合治疗功能性消化不良的临床疗效。方法将幽门螺旋杆菌阳性FD患者108例随机分为治疗组53例和对照组55例,治疗组采用六味安消胶囊加标准三联抗幽门螺旋杆菌疗法治疗,对照组仅采用六味安消胶囊加雷贝拉唑治疗。结果治疗组幽门螺旋杆菌根除率83%,对照组为9%,两组幽门螺旋杆菌根除率比较有显著性差异(P<0.01)。症状改善率及0.5a持续症状缓解率治疗组均优于对照组(P<0.05或0.01)。结论幽门螺旋杆菌阳性FD患者采用中西药结合方法根除幽门螺旋杆菌治疗,可明显改善症状。
Objective To explore the clinical efficacy of traditional Chinese and western medicine in treating functional dyspepsia. Methods 108 patients with Helicobacter pylori-positive FD were randomly divided into treatment group (n = 53) and control group (n = 55). The treatment group was treated with Liuwei Anxiao Capsule plus standard triple anti-Helicobacter pylori, while the control group was treated with Liuwei Anxiao capsule Veraprazole treatment. Results Helicobacter pylori eradication rate was 83% in the treatment group and 9% in the control group. There was significant difference between the two groups in the eradication rate of Helicobacter pylori (P <0.01). Symptom improvement rate and 0.5a sustained symptom relief rate were better than the control group (P <0.05 or 0.01). Conclusion Helicobacter pylori-positive FD patients with Chinese and Western medicine combined with eradication of Helicobacter pylori treatment can significantly improve the symptoms.