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本综合征是一种伴有特异性全身症状的急性弥漫性葡萄膜炎,它是选择性侵犯全身黑色素细胞的系统性疾病。由于在本病的早期常有明显的脑膜刺激征或脑炎征状,故又名葡萄膜脑膜综合征(uveo—meningitic syndrome)、葡萄膜脑膜炎(uveo—meningitis)、葡萄膜脑炎综合征(uveo—encephalitic syndrome)、葡萄膜大脑炎(uveo—encephalitis)、葡萄膜脑膜脑炎(uveo—meningo—encephalitis)。由于本综合征除眼、脑症状外还可出现耳的听力障碍和皮肤白斑、白毛、脱发等,故又称其为眼—脑—耳—皮综合征。早在1906年瑞士的Vogt氏就描述了一例伴有脱发,眉毛、睫毛和头发变白的两眼虹膜睫状体炎。1929年日本的小柳氏复习了有关文献对16例进行了详细的描述,
This syndrome is a combination of specific systemic symptoms of acute diffuse uveitis, which is a systemic disease that selectively invades systemic melanocytes. Uveo-meningitic syndrome, uveo-meningitis, uveal encephalitis syndrome, a form of uveo-meningitic syndrome, also known as uveo-meningitic syndrome, uveo-encephalitic syndrome, uveo-encephalitis, uveo-meningo-encephalitis. As the syndrome in addition to the eye, brain symptoms can appear outside the ear hearing impairment and skin white, white hair, hair loss, it is also known as the eye - brain - ear - skin syndrome. As early as 1906, Vogt in Switzerland described an example of bilateral iridocyclitis with hair loss, eyebrows, eyelashes and hair whitening. In 1929 Japan’s Koyanagi reviewed the literature on the 16 cases were described in detail,