本文对109名8～21岁的健康男性儿童青少年进行了急性饮食盐负荷下肾脏排钠功能的研究。结果表明,有原发性高血压家族史的血压正常对象,相对于无家族史的对象负荷后尿排钠量少,负荷排钠反应慢且弱。结果提示:有原发性高血压家族史的儿童,可能在高血压病发病前就已存在遗传性肾脏排钠功能缺陷。 In this paper, 109 healthy children and adolescents aged from 8 to 21 years were studied for renal sodium excretion function under acute salt diet. The results showed that the normotensive subjects with a family history of essential hypertension had less urinary sodium excretion and a slower and weaker response to sodium load than those without family history. The results suggest that: children with a family history of essential hypertension may have had a genetic defect of sodium excretion of sodium prior to the onset of hypertension.