侧向加压充填技术和垂直加压充填技术对根管微渗漏影响的对比研究.目的:首次采用葡萄糖渗漏模型(GPM)对比研究在有根充糊剂和没有根充糊剂的情况下垂直加压充填技术和侧向加压充填技术对根管微渗漏的影响.方法:选取53颗直根管上前牙,根管预备后随机分为5组,A组(14颗)用热牙胶垂直加压加AH Plus充填,B组(8颗)仅用热牙胶垂直加压充填,C组(13颗)用侧方加压加AH Plus充填,D组(8颗)仅用侧方加压充填技术,E组10颗)为阴性对照组,用粘蜡充填根管,牙根外表面及根尖孔处涂二层指甲油.于第7、14、21、28天用葡萄糖氧化酶法检测从冠方向根方漏出的葡萄糖量.结果:采用重复测量方差分析,发现第7、14、21、28天A、C组微渗漏值有显著性差异(P＜0.001).各时间点C、D组比较有显著性差异(P＜0.001).第7、14天及第21、28天各组内比较无显著性差异(P＞0.05),但各组第14天与第21天比有显著性差异(P＜0.05).结论:侧方加压充填技术封闭根管的能力优于垂直加压充填技术及固核载体充填技术,而后两种充填技术封闭根管的能力相当.“,”Objective: The aim of this study was to assess the sealing ability of lateral compaction technique and vertical compaction technique using glucose penetration model. Glucose penetration model (GPM) has only twice been used earlier, hence the second aim of the study was to correlate the results of this study to other results and to validate the efficacy of GPM. Materals and Methods: Fifty three straight anterior human maxillary teeth were randomly divided into five groups.Root canals were prepared using crown down technique. Group A had fourteen teeth. They were compacted using vertical compaction technique. AH plus was used as root canal sealer. Group B had eight teeth. These were also compacted with vertical compaction but without AH plus. Group C had thirteen teeth. All the teeth in group C were compacted using lateral compaction using AH Plus. Group D had eight teeth. The teeth in this group were compacted using lateral compaction technique without AH plus. Group E had ten teeth. This group was assigned as negative control group. The specimen of the negative control group were completely coated with aryldite. The roots of the experimental groups were covered with aryldite, except for the root canal orifices, and apical apices. The coronal end of the decoronated tooth was connected to a plastic tube that contained 18% glucose solution. Leakage along the root filling was measured by the concentration of glucose in apical reservoir at 7, 14, 21 and 28 days intervals respectively after treatment. Results: Using repeated measure ANOVA, the leakage was significantly different among test groups A and C at 7, 14, 21 and 28 days interval respectively(P ＜ 0.001). Data from Groups C and D also varied significantly. No statistical difference was found between groups A, B and D. Glucose concentrations at 21,28 days were higher than that at 7, 14 days in all of the four groups. Conclusion:The sealing ability of lateral compaction technique was found to be better than vertical compaction. There was a continuous increase in apical microleakage at 7th, 14th, 21st and 28th day. There was a sudden increase in apical microleakage on the 21st and 28th day.