多囊卵巢综合征(PCOS)是引起育龄妇女不孕的主要原因。近年来动物实验揭示:出生前暴露于过多雄激素中,可导致雌性胎儿成年后产生PCOS样改变,包括高雄激素血症、LH/FSH比值升高、高胰岛素血症、卵巢多囊样改变和无排卵等。因此,有学者提出胎儿期雄激素过多可能是PCOS的致病因素之一,即胎儿时期受高雄激素的影响可导致成年后产生PCOS的症状与体征。 Polycystic ovary syndrome (PCOS) is the main cause of infertility in women of childbearing age. In recent years, animal experiments revealed that exposure to excess androgen before birth may lead to PCOS-like changes in adult female fetuses, including androgenic hyperandrogenism, elevated LH / FSH ratio, hyperinsulinemia, and polycystic ovary changes And no ovulation and so on. Therefore, some scholars have suggested that excessive androgen in the fetus may be one of the causative factors of PCOS, that is, the influence of hyperandrogenism in fetus can lead to the symptoms and signs of PCOS after birth.