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目的 研究齿龈内阿米巴 (Entamoeba gingivalis,E.g.)的致病作用及其与牙周病的关系。 方法 大鼠经免疫抑制剂处理 1wk,并于切牙颈部结扎钢丝后 ,随机分为 3组 ,分别于龈缘涂抹 E.g.、共生菌 (symbioticbacteria,s.b.)及生理盐水 ,观察各组大鼠牙周组织发病情况 ,并查脓液中有无活的病原体。 结果 E.g.组大鼠牙周组织发病率高于 s.b.组和对照组 (P<0 .0 5 ) ,s.b.组大鼠发病率亦高于对照组 (P<0 .0 5 ) ,脓液镜检或经培养均查见相应的病原体。 结论 齿龈内阿米巴是一种条件致病病原体 ,当宿主免疫力下降时 ,在口腔细菌协同作用下致使宿主产生牙周病
Objective To study the pathogenicity of Entamoeba gingivalis (E.g.) And its relationship with periodontal disease. Methods The rats were treated with immunosuppressive agents for 1 week and ligated at the neck of incisors. The rats were randomly divided into 3 groups. Eg, gi (symbiotic bacterium, sb) and saline were applied to the gingival margin. Week of tissue disease, and check whether there is live in the pus pathogens. Results The incidence of periodontal tissue in Eg group was higher than that in sb group and control group (P <0.05). The incidence of sb group was also higher than that in control group (P <0.05) Or through the culture see the corresponding pathogens. Conclusion Intra-A. gingivalis is a causative causative pathogen. When the host immunity is decreased, it causes the host to produce periodontal disease under the synergistic effect of oral bacteria