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目的研究HIV夫妻间传播率,为预防控制性传播提供科学依据。方法选择一方HIV阳性,另一方HIV阴性,且没有静脉吸毒、多性伴、有偿献血、输血等HIV感染高危行为史,有稳定婚姻的夫妻,双阳夫妻采用回顾性队列研究方法,单阳家庭采用采用前瞻性队列方法。结果夫妻间传播率为30.00%(39/130),男传女传播率为33.78%(25/74),女传男传播率为25.00%(14/56)。夫妻性生活年限越长、先症病例感染后与配偶开始同居年龄越大,性行为频次越高,传播率越高。多因素非条件Logistic回归分析显示,性别、夫妻性生活年限、年龄及性行为频次均为夫妻HIV传播的相关因素。结论 HIV夫妻传播率较高,与性别、夫妻性生活年限、年龄及性行为频次有关。加大早期发现力度,采取有针对性的干预措施,才能有效遏制HIV性传播。
Objective To study the HIV transmission rate among couples and provide a scientific basis for the prevention of sexually transmitted diseases. Methods One HIV positive, the other HIV negative, and no intravenous drug use, multiple sexual partners, paid blood donation, blood transfusions and other high-risk HIV infection history, stable marriage couples, Shuangyang couples with a retrospective cohort study, single-Yang family use Using a prospective cohort method. Results The rate of inter-marital transmission was 30.00% (39/130), male transmission rate was 33.78% (25/74), female transmission rate was 25.00% (14/56). The longer the sexual life of a couple, the first case of infection and spouse after cohabitation with the older, the higher the frequency of sexual behavior, the higher the rate of transmission. Multivariate non-conditional Logistic regression analysis showed that gender, marital life span, age and frequency of sexual behavior were the related factors of HIV transmission. Conclusion The HIV transmission rate among couples is high, which is related to gender, marital life span, age and frequency of sexual behavior. Increasing the early detection efforts to take targeted interventions in order to effectively curb the transmission of HIV.