皮内接种卡介苗引起的典型原发综合征,包括注射部位的皮肤结节和引流淋巴结的肿大。少数人对此大量细菌可产生局部溃疡、皮下脓肿或化脓性淋巴结炎。如果将菌苗注入皮下或被接种者结核菌素反应为阳性者,则上述并发症就更易发生。过去曾在局部试用 PAS 或异烟肼粉治疗,但效果都不甚理想。最近,Power 及其同事们用红霉素口服试验治疗6例病人,其中3例为接种后脓肿形成,3例溃疡有分泌物 Typical primary syndromes caused by intradermal BCG vaccination include skin nodules at the site of injection and swelling of the draining lymph nodes. A small number of people on this large number of bacteria can produce local ulcers, subcutaneous abscess or purulent lymphadenitis. The above complication is more likely to occur if the vaccine is injected subcutaneously or if the vaccinee is positive for tuberculin reaction. In the past in the local trial PAS or isoniazid powder treatment, but the effect is not satisfactory. Recently, Power and colleagues treated six patients with erythromycin in an oral trial, three of which were post-vaccination abscesses and three of which had secretions