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乙烯-醋酸乙烯酯共聚物[ethylenevinyl acetate copolymer(EVA)]是一种能用热处理的、柔软的、无毒的廉价材料,具有良好的生物适应性,可作为生物医学的植入或插入用制剂的载体或表面应用药物释放器的载体。本文研究了用EVA膜控制去氢氢化可的松的释放情况。研究中使用的EVA共聚物的维生素A(VA)含量为8~33%(w/w)。药膜的制备:将药物粉末溶于二氯甲烷或甲苯中,再将EVA共聚物溶于该药物溶液(50℃)中,使EVA浓度为5%(w/v)。将此混合液倒入玻璃盘中,室温下挥发溶剂,脱
Ethylene-vinyl acetate copolymer (EVA) is a heat-treatable, soft, non-toxic, inexpensive material with good biocompatibility that can be used as a biomedical implant or insert formulation Carrier or surface-application drug release. In this paper, the release of hydrogenated cortisone with EVA film was studied. The EVA copolymer used in the study had a Vitamin A (VA) content of 8 to 33% (w / w). Preparation of the membrane: The drug powder is dissolved in methylene chloride or toluene, and the EVA copolymer is dissolved in the drug solution (50 ° C) so that the EVA concentration is 5% (w / v). Pour the mixture into a glass dish and evaporate the solvent at room temperature