细胞恶性转化是指正常细胞受致癌因子的作用转变成恶性细胞的过程,它既能在体内发生,也能在体外将培养细胞诱发。要识别体内发生的恶性转化的特征是十分困难的,这是因为致癌因子所引起的细胞转化与中毒作用不易区别,而且在转化过程中会受到诸如动物的营养状况、激素水平、内源性 Malignant transformation of cells refers to the process by which normal cells are transformed into malignant cells by the action of carcinogenic factors. It can occur both in vivo and in vitro. It is very difficult to identify the characteristics of malignant transformation that occur in vivo. This is because the cell transformation and poisoning caused by carcinogenic factors are not easy to distinguish, and they are subject to such nutritional status, hormone levels, and endogenous levels of the animal during transformation.