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通过甲基丙烯酸甲酯染毒的雄鼠精子畸形试验、精子计数、活动精子百分率的检查、睾丸和附睾的脏器系数及光、电镜病理学检查以及血清睾酮（Ｔ） 、黄体生成素（ＬＨ） 的检测， 研究甲基丙烯酸甲酯对雄性大鼠生殖功能的影响。实验结果表明， 中、高剂量组（１－６８ ｇ／ｋｇ 和２－８０ ｇ／ｋｇ 组） 的精子数明显减少而精子畸形率明显增高； 高剂量组的活动精子百分率下降， 且染毒雄鼠的体重增重减少， 睾丸脏器系数显著下降， 血清Ｔ 下降； 中剂量组的血清ＬＨ 明显升高。提示甲基丙烯酸甲酯对雄鼠生殖功能有损害作用。
The results of sperm abnormality test, sperm count, percentage of active sperm, testicular and epididymis organ coefficient, light and electron microscopy pathological examination, serum testosterone (T), luteinizing hormone (LH) ) To detect the effect of methylmethacrylate on the reproductive function of male rats. The results showed that sperm count of sows in medium and high dose groups (1-68 g / kg and 2-80 g / kg) decreased significantly while sperm deformity rate increased significantly; the percentage of active sperm in high dose group decreased, Rats weight gain decreased, testicular organ coefficient decreased significantly, serum T decreased; middle dose group serum LH was significantly higher. Tip methyl methacrylate male mice reproductive function damage.