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本文按照新生儿溶血症(Hemolytic Disease of Newborn)HDN中,三项试验诊断标准,十年中共检出新生儿溶血症282例。男性156例,占55.31％,女性126例,占44.68％。年龄在出生后9小时至12天。在282例新生儿溶血症,抗体依次为抗A 124例(44％)、抗B 97例(34％)、抗D 45例(16％)、抗E 9例(3％)、抗cE 5例(2％)、抗Ce及抗C各1例。所占比例分别为:43.97％、34.39％、15.9％、3.19％、1.77％、0.71％。直接抗人球蛋白试验阳性115例占40.78％,释放试验阳性265例,占94.15％。游离试验阳性249例,占88.3％。结果提示,除ABO以外,Rh血型系统是引起上海地区HDN的主要血型抗体。对高危孕妇进行血清学检测来预报HDN,以便做到早发现、早治疗。
This article according to the neonatal hemolytic disease (Hemolytic Disease of Newborn HDN, the three test diagnostic criteria, a total of 282 cases of neonatal hemolytic disease were detected. 156 males, accounting for 55.31%, 126 females, accounting for 44.68%. The age is 9 hours to 12 days after birth. In 282 cases of neonatal hemolytic disease, the antibodies were anti-A 124 (44%), anti-B 97 (34%), anti- D 45 (16%), anti-E 9 (3%), anti-cE 5 Cases (2%), anti-Ce and anti-C in 1 case. The proportions are as follows: 43.97%, 34.39%, 15.9%, 3.19%, 1.77%, 0.71% respectively. Direct anti-human globulin test positive 115 cases accounted for 40.78%, release test positive 265 cases, accounting for 94.15%. Free test positive 249 cases, accounting for 88.3%. The results suggest that, in addition to ABO, Rh blood group system is caused by HDN in Shanghai major blood group antibodies. High-risk pregnant women serological test to predict HDN, in order to achieve early detection and early treatment.