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目的 :探讨血清中微量元素水平与泸州地区男性不育症的关系。方法 :对 87例已确诊男性不育症的患者行常规精液检查 ,同时对其血清中锌、铁、铜、镉、锰的含量进行测定 ,并与 32例健康已育男性进行对照。结果 :不育症组血锌含量显著低于对照组 (P <0 .0 1) ,血铜含量高于对照组 (P <0 .0 5 ) ,血铜 锌比值降低 (P <0 .0 5 ) ,血镉 锌比值降低 (P <0 .0 1)。血铁、锰、镉含量在两组间无显著差异 (P >0 .0 5 )。不育症组中随精子数量的减少 ,血锌含量显著降低 ,血铜含量及血铜 锌比值明显升高 ,差异均有显著性 (P <0 .0 5 )。结论 :血锌含量的降低、血铜含量升高可能与泸州地区原发性男性不育症有关。测定血清中微量元素水平对男性不育症的诊治有指导意义
Objective: To investigate the relationship between serum trace element levels and male infertility in Luzhou area. Methods: Eighty-seven patients with confirmed male infertility underwent routine semen examination, and the levels of serum zinc, iron, copper, cadmium and manganese were measured and compared with 32 healthy male infertile men. Results: The content of blood zinc in infertility group was significantly lower than that in control group (P <0.01), blood copper content was higher than that in control group (P <0.05) 5), blood cadmium-zinc ratio decreased (P <0.01). There were no significant differences in serum iron, manganese and cadmium levels between the two groups (P> 0.05). In the infertility group, with the decrease of the number of sperm, the content of blood zinc decreased significantly, the content of blood copper and the ratio of blood to copper and zinc increased obviously, the difference was significant (P <0.05). Conclusion: The decrease of blood zinc level and the increase of blood copper level may be related to the primary male infertility in Luzhou. Determining serum trace element levels has guiding significance for the diagnosis and treatment of male infertility