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二硝基氯苯滴背致敏后，经肛灌肠以制作病理模型。造模完成后１２天内，３６只大鼠中３２只检见典型的结肠溃疡。以“肠道流体推进检测系统”发现，该期病鼠离体结肠的基础腔内压倾向降低、袋状运动紊乱；其推进行为异常有复合波节作过高、肠道运动功能衰弱、肛向推进出超三个类型；可解释有关结肠疾病大便改变的部分机制。造模后织１３～５０天为溃疡修复期，该期结肠运动倾向好转。药理实验显示，动脉灌注２×１０￣（－５）ｍｏｌ／Ｌ白术羟内酯对病鼠节律过高的结肠推进行为有抑制作用；而２×１０￣（－５）ｍｏｌ／Ｌ二氢黄酮Ｂ３则对运动功能减弱的结肠有动力作用。两者可从不同方向有效调整肠道功能；可供开发利用。
Dinitrochlorobenzene drops back sensitized, anal enema to make the pathological model. Within 12 days after model establishment, 32 of the 36 rats detected typical colonic ulcers. The “intestinal fluid advancement detection system” found that this period of disease in vitro colon basilar intracavitary pressure tends to reduce the bag-like movement disorders; the promotion of abnormal behavior complex wave node too high for bowel function weakness, anal To push out over three types; part of the mechanism that can explain stool changes related to colon disease. Weaving 13 to 50 days after the repair of ulcer repair period, the trend of colorectal movement improved. Pharmacological experiments showed that intra-arterial infusion of 2 × 10 ~ (-5) mol / L albuterol had inhibitory effect on colonic propulsive behavior in mice with high rhythm; while 2 × 10 ~ (-5) mol / L flavanone B3 on the weakened motor function of the colon has a dynamic effect. Both can effectively regulate intestinal function in different directions; for development and utilization.