论文部分内容阅读
目的探讨糖尿病患者实施血脂调控的预后效果。方法 100例糖尿病患者,随机分为观察组和对照组,各50例。对照组给予口服降糖药或注射胰岛素治疗,观察组在此基础上联用阿伐他汀治疗。分别于治疗前、治疗后1周、治疗后1个月、治疗后3个月检测两组患者空腹血糖(FBG)、餐后2 h血糖(2 h PBG)、糖化血红蛋白(Hb A1c)、空腹胰岛素(FINS)、总胆固醇(TC)以及甘油三酯(TG)水平,并进行比较。结果治疗后1、3个月,两组患者FBG、2 h PBG、Hb A1c、FINS、TG以及TC水平均优于治疗前,差异具有统计学意义(P<0.05);治疗后1个月,观察组患者FBG、2 h PBG、Hb A1c、FINS、TG以及TC水平分别为(6.09±0.97)mmol/L、(8.49±1.36)mmol/L、(5.69±1.13)%、(7.96±1.05)m U/L、(1.67±0.58)mmol/L、(5.09±0.62)mmol/L,治疗3个月上述指标分别为(6.07±0.95)mmol/L、(8.38±1.28)mmol/L、(5.63±1.09)%、(8.19±1.68)m U/L、(1.61±0.55)mmol/L、(4.97±0.59)mmol/L,均明显优于对照组的(7.72±1.35)mmol/L、(9.61±1.65)mmol/L、(8.15±1.62)%、(6.84±1.16)m U/L、(2.38±0.85)mmol/L、(5.63±0.87)mmol/L及(7.58±1.23)mmol/L、(9.49±1.56)mmol/L、(8.09±1.58)%、(6.72±1.23)m U/L、(2.19±0.83)mmol/L、(5.62±0.85)mmol/L,差异具有统计学意义(P<0.05)。结论对糖尿病患者实施血脂调控更有助于改善患者的血糖状况,值得广泛推广。
Objective To investigate the prognosis of patients with diabetes mellitus undergoing lipid regulation. Methods 100 cases of diabetic patients were randomly divided into observation group and control group, 50 cases each. The control group was given oral hypoglycemic agents or insulin injections, and the observation group was treated with atorvastatin on this basis. The levels of fasting blood glucose (FBG), 2-hour postprandial blood glucose (2 h PBG), Hb A1c, fasting blood glucose Insulin (FINS), total cholesterol (TC) and triglyceride (TG) levels, and compared. Results The levels of FBG, 2 h PBG, Hb A1c, FINS, TG and TC in both groups were significantly better than those before treatment at 1 and 3 months after treatment (P <0.05). One month after treatment, The levels of FBG, 2 h PBG, Hb A1c, FINS, TG and TC in observation group were (6.09 ± 0.97) mmol / L, (8.49 ± 1.36) mmol / L and (5.69 ± 1.13)% and (7.96 ± 1.05) (6.07 ± 0.95) mmol / L and (8.38 ± 1.28) mmol / L respectively after treatment for 3 months (m / L, 1.67 ± 0.58 mmol / L and 5.09 ± 0.62 mmol / 5.61 ± 1.09%, 8.19 ± 1.68 mU / L, 1.61 ± 0.55 mmol / L and 4.97 ± 0.59 mmol / L, respectively, which were significantly higher than those of the control group (7.72 ± 1.35 mmol / L, (9.61 ± 1.65) mmol / L, (8.15 ± 1.62)%, (6.84 ± 1.16) mU / L, (2.38 ± 0.85) mmol / L, (9.49 ± 1.56) mmol / L, (8.09 ± 1.58)%, (6.72 ± 1.23) mU / L, (2.19 ± 0.83) mmol / L, and (5.62 ± 0.85) mmol / L respectively Significance (P <0.05). Conclusion The implementation of blood lipid regulation in diabetic patients is more helpful to improve the blood glucose status of patients, which should be widely promoted.