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目的:了解我院药品不良反应(ADR)发生的规律与特点,为临床安全用药提供参考。方法:对我院2009年1月1日～2009年12月20日收集到的252例ADR报告,从报告数量、报告来源、药品种类、给药途径、涉及器官或系统及临床表现等方面进行统计、分析。结果:不良反应报告女性多于男性,60以上患者为敏感人群。静脉滴注是发生ADR的主要给药途径,252例ADR涉及120种药品,其中主要是抗菌药(133例,41个品种)和中药制剂(30例,20个品种),损及皮肤及附件的ADR构成比为46.82%。结论:医院应进一步加强ADR监测与医疗监管工作,促进合理用药。
Objective: To understand the rules and characteristics of adverse drug reaction (ADR) in our hospital and provide reference for clinical safety medication. Methods: A total of 252 ADR reports collected from January 1, 2009 to December 20, 2009 in our hospital from the aspects of the number of reports, the sources of reports, the types of drugs, the route of administration, the organ or systemic and clinical manifestations Statistical Analysis. Results: More women than men were reported as adverse reactions, and more than 60 patients were sensitive. Intravenous infusion is the main route of ADR. 252 cases of ADR involved 120 kinds of drugs, mainly antibacterial drugs (133 cases, 41 varieties) and traditional Chinese medicine preparations (30 cases, 20 varieties), which damaged the skin and appendix The ADR composition ratio was 46.82%. Conclusion: The hospital should further strengthen the monitoring of ADR and medical supervision, and promote rational drug use.