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目的:探讨换血疗法的有效性和安全性。方法:选取2012年1月至2016年11月在安徽医科大学第二附属医院新生儿科住院治疗的40例新生儿换血病例作为研究对象,比较换血前后的血生化及血常规等指标。结果:换血后总胆红素、间接胆红素均明显下降(P<0.01),总胆红素换出率为42.2%。WBC、PLT、血钙有所下降(P<0.01);血糖水平升高(P<0.01)。结论:换血疗法可迅速降低血清胆红素,对血液系统及内环境影响较为常见,换血过程中及换血后需密切监测相关指标。
Objective: To explore the effectiveness and safety of transfusion therapy. Methods: From January 2012 to November 2016, 40 newborns transfused from neonates in the Department of Neonatology, the Second Affiliated Hospital of Anhui Medical University were enrolled in this study. Blood biochemistry and blood routine indexes were compared before and after transfusions. Results: Total bilirubin and indirect bilirubin were significantly decreased (P <0.01) after exchange transfusion and total bilirubin exchange rate was 42.2%. WBC, PLT, blood calcium decreased (P <0.01); blood glucose levels increased (P <0.01). Conclusion: The exchange transfusion therapy can rapidly reduce the serum bilirubin, which has a relatively common effect on the blood system and the internal environment. It is necessary to closely monitor the relevant indexes during the transfusion and transfusion.