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目的:探析侵袭性肺真菌病诊断中真菌抗原检测的临床价值。方法:选取2013年5月-2014年12月本院收治的142例确诊侵袭性肺真菌病患者及47例临床诊断侵袭性肺真菌病患者为研究资料,对患者的真菌病诊断方法、真菌抗原的检测方法阳性率、特异性等进行回顾性分析。结果:病理确诊19例,拟诊确诊89例,临床诊断94例;甘露聚糖抗原检测的阳性率为70.21%,半乳甘露聚糖(GM)检测的阳性率为25.53%,隐球菌荚膜多糖抗原检测的阳性率为4.26%。结论:侵袭性肺真菌病诊断中应用真菌抗原检测可为真菌抗原的早期诊断提供指导性的建议。
Objective: To investigate the clinical value of fungal antigens in the diagnosis of invasive pulmonary mycosis. Methods: From May 2013 to December 2014 in our hospital, 142 patients with confirmed invasive pulmonary mycosis and 47 patients with clinically diagnosed invasive pulmonary mycosis were selected as research data. The diagnosis of mycosis, fungal antigens The detection method of positive rate, specificity, etc. were retrospectively analyzed. Results: 19 cases were pathologically diagnosed, 89 were diagnosed clinically and 94 cases were diagnosed clinically. The positive rate of mannan polysaccharide antigen was 70.21%, the positive rate of galactomannan (GM) was 25.53% The positive rate of polysaccharide antigen detection was 4.26%. Conclusion: The detection of fungal antigens in the diagnosis of invasive pulmonary mycosis can provide guidance for the early diagnosis of fungal antigens.