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目的:探讨乳腺癌钼靶X线表现与雌激素受体(ER)表达之间的相关性。方法:将180例乳腺癌患者X线征象中钙化、毛刺、结构紊乱、病变密度增高、边缘浸润及是否同时合并乳腺囊性增生症与经免疫组织化学染色测定ER表达进行对照研究。结果:180例乳腺癌患者中,有钙化者98例,占54.4%;出现毛刺征75例,占41.7%;结构紊乱72例,占40%;病变区表现为高密度90例,占50%;有边缘浸润者96例,占53.5%;乳腺癌同时合并乳腺囊性增生症91例,占50.6%。ER表达阳性100例,占55.6%。毛刺征、边缘浸润征组及同时合并乳腺囊性增生症者ER阳性表达率高;结构紊乱、病变区高密度ER阳性表达率低,钙化征与ER表达无关。结论:乳腺癌钼靶X线征象在一定程度上反映了ER表达状态。
Objective: To investigate the correlation between mammographic X-ray findings and estrogen receptor (ER) expression in breast cancer. Methods: Fluorescence, burr, structural disorder, increased lesion density, edge infiltration, and simultaneous breast cystic hyperplasia were detected in 180 patients with breast cancer. The expression of ER was determined by immunohistochemical staining. Results: In 180 patients with breast cancer, there were 98 cases of calcification, accounting for 54.4%; there were 75 cases of spiculations, accounting for 41.7%; structural disorders in 72 cases, accounting for 40%; lesions showed high density in 90 cases, accounting for 50% There were 96 patients with marginal infiltration, accounting for 53.5%; breast cancer combined with 91 cases of breast cystic hyperplasia, accounting for 50.6%. Positive ER expression was 100 cases, accounting for 55.6%. The ER positive expression rate was higher in the burr sign, edge infiltration syndrome, and concurrent cystic hyperplasia group; structural disorder, high density ER positive expression rate in the lesion area was low, and the calcification sign was not related to ER expression. Conclusion: The mammographic X-ray findings of breast cancer reflect the status of ER expression to some extent.