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人参在中医药中应用已有五千余年历史,早就记载它能延年益寿。近二十年研究认为人参具有防御应激、增加基础代谢、恢复疲劳、激活中枢神经、刺激内分泌、抗癌、治糖尿病、降压、有利于组织胺和5-羟色胺的分泌等作用。有关人参在体内的生理、生化研究大部分都集中在人参的皂甙部分。作者最近从朝鲜红参的非皂甙部分得到具有生理活性的物质,为酸性多聚糖,它能抑制荷瘤小鼠腹水中类毒激素-L的脂质分解作用。另外,还发现朝鲜红参中含有腺苷和焦性谷氨酸(pyroglu-tamic acid),它们能抑制肾上腺素诱导的脂质分解作用和刺激胰岛素诱导的脂质生成作用。
Ginseng has been used in Chinese medicine for more than 5,000 years and it has long been documented that it can prolong life. In the past two decades, ginseng has been found to have defensive stress, increase basal metabolism, restore fatigue, activate central nervous system, stimulate endocrine, anticancer, treat diabetes, reduce blood pressure, and facilitate the secretion of histamine and serotonin. Most of the physiology and biochemistry studies of ginseng in vivo have focused on the saponin part of ginseng. The author recently obtained a physiologically active substance from the non-saponifiable part of Korean red ginseng, which is an acidic polysaccharide, which can inhibit the lipid decomposition of ghrelin-L in the ascitic fluid of tumor-bearing mice. In addition, it has been found that Korean red ginseng contains adenosine and pyroglu-tamic acid, which can inhibit adrenaline-induced lipolysis and stimulate insulin-induced lipid production.