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有人观察到人疱疹病毒6型(HHV-6)通常存在于唾液中,并且从唾液中分离出该病毒的阳性率很高。为证实这一设想,作者用原位杂交及免疫组织化学染色法检测唾液腺,以明确HHV-6感染证据;还用同样方法检测唾液腺,以明确巨细胞病毒(CMV)感染的证据。用于原位杂交及免疫组织化学染色的石蜡切片是13例有良性肿瘤及结石的唾液腺(9例下颌下腺,4例腮腺)的活检组织,对照组为1例有CMV肺炎的艾滋病患者及1
It has been observed that human herpes virus type 6 (HHV-6) is commonly found in saliva and that the virus is highly positive in saliva. To confirm this idea, the authors used in situ hybridization and immunohistochemical staining of salivary glands in order to confirm the evidence of HHV-6 infection. Salivary glands were also detected in the same way in order to clarify the evidence of cytomegalovirus (CMV) infection. Paraffin sections for in situ hybridization and immunohistochemical staining were biopsies of 13 salivary glands (9 submandibular glands, 4 parotid glands) with benign tumors and stones, and 1 control group with AIDS with CMV pneumonia and 1