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目的了解医院药品不良反应(ADR)的发生特点和规律,为临床的合理用药提供参考。方法收集某院2014年上报的209例ADR报表,并进行回顾性统计分析。结果 209例ADR报告中,发生ADR的女性患者多于男性患者(136例:73例,1.86:1);60岁以上老年患者的ADR发生率较高(81例,38.76%);静脉滴注是引起ADR最多的给药途径(131例,62.68%);引发ADR最多的药物是抗菌药物(46例,22.0%);ADR临床表现以皮肤及其附件的损害最为常见(78例,37.32%)。结论临床应进一步加强ADR的监测,促进合理用药,保障患者的用药安全。
Objective To understand the characteristics and regularity of hospital adverse drug reaction (ADR) and provide a reference for clinical rational drug use. Methods A total of 209 cases of ADR reported by a hospital in 2014 were retrospectively analyzed. Results In 209 ADR cases, there were more female patients than male patients (136 cases: 73 cases, 1.86: 1), ADR was higher in patients over 60 years old (81 cases, 38.76%), (131 cases, 62.68%). The drug that caused the most ADR was antimicrobial drug (46 cases, 22.0%). The clinical manifestations of ADR were the most common lesions of skin and its appendages (78 cases, 37.32% ). Conclusion Clinical monitoring of ADR should be further strengthened to promote rational drug use and ensure the safety of patients.