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作者介绍了1979～1982年采用三结合疗法中术前能行CT检查的31例上颌窦鳞癌患者资料。男21,女10,平均年龄59.8岁。病检均为鳞癌(高分化8例,中等分化18例,低分化5例)。参考术前CT,按TNM分类,T_24例,T_317例,T_410例;T_3+T_4共27例,占87％。全组病例均为N_1,无M_1。临床分期为:Ⅱ期3例,Ⅲ期18例,Ⅳ期10例。全部病例均采用手术、放疗、局部动脉持续灌注化疗相结合的方法。手术注意保持上颌窦功能和形态,以尽可能摘除肿瘤为原则,行上颌骨部分切除术。放疗一次量为2Gy,每周5次。平均总量为37.8Gy。化疗和术后放疗同时进行。抗癌药5-FU由颞浅动脉持续灌注。平均给药量为2403mg。
The authors presented data on 31 patients with maxillary sinus squamous cell carcinoma who were able to perform CT examinations preoperatively in the triple combination therapy from 1979 to 1982. Male 21, female 10, average age 59.8 years old. The disease tests were squamous cell carcinoma (highly differentiated 8 cases, moderately differentiated 18 cases, poorly differentiated 5 cases). Reference preoperative CT, according to TNM classification, T_24 cases, T_317 cases, T_410 cases; T_3+T_4 total 27 cases, accounting for 87%. All cases were N_1, no M_1. The clinical stage was: 3 cases of stage II, 18 cases of stage III, and 10 cases of stage IV. All cases were treated with surgery, radiotherapy, and local arterial continuous infusion chemotherapy. Surgical attention to maintain maxillary sinus function and morphology, in order to remove the tumor as far as possible, the principle of partial maxillofacial resection. The amount of radiotherapy once was 2Gy, 5 times a week. The average total amount is 37.8Gy. Chemotherapy and postoperative radiotherapy are performed simultaneously. The anticancer drug 5-FU was continuously perfused through the superficial temporal artery. The average dose was 2403 mg.